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Cause Allergies


2. Cause Allergies

To help answer this question, let us look at some examples of common household. A few months after the arrival of a cat in the house, the father began to get itchy eyes and episodes of sneezing. One of three children develops coughing and wheezing, especially when the cat into her bedroom. Mother and two other children did not experience any reaction to the presence of cats. How do we explain this?

The immune system is a defense mechanism organized by the body against foreign invaders, particularly infections. His job is to recognize and react to these foreign substances, called antigens. Antigens are substances that can cause the production of antibodies. Antigens may or may not lead to an allergic reaction. Allergens are certain antigens that cause allergic reactions and the production of IgE.

The purpose of the immune system is to mobilize its strength on the scene of the attack and destroy the enemy. One way to do this is to create protective proteins called antibodies specifically directed against certain foreign substances. These antibodies, or immunoglobulins (IgG, IgM, IgA, IgD), are protective and help destroy foreign particles to attach themselves to the surface, thus making easier the other immune cells to destroy it. However people who are allergic, develop a specific type of antibody called immunoglobulin E, or IgE, in response to a specific foreign substance that is generally harmless, such as cat dander. In summary, immunoglobulins are a group of protein molecules that work as antibodies. There are 5 kinds of different types: IgA, IgM, IgG, IgD, and IgE. IgE is the allergy antibody.

In the example of animals cats, father and youngest daughter developed IgE antibodies in large quantities directed against cat allergen, the cat dander. Father and daughter are now sensitized or prone to develop allergic reactions on subsequent and repeated exposure to cat allergen. Typically, there is a period of "sensitization" ranging from months to years before an allergic reaction. While it may occasionally occur an allergic reaction in the first exposure to the allergen, certainly before there was contact so that the immune system is reacting this way.

IgE is an antibody that is owned by all of us in small quantities. People who are allergic, however, produce IgE in large amounts. Normally, this antibody is important in protecting us from parasites, but not from cat dander or allergens. During the sensitization period, cat dander IgE is overproduced and coats certain cells that contain a potentially explosive chemicals. These cells are capable of causing an allergic reaction on subsequent exposure to dander. This is caused by the reaction of the cat dander with the dander IgE irritates the cells and leads to the release of various chemicals, including histamine. These chemicals, in turn, causes inflammation and allergy symptoms are typical. This is how the immune system becomes exaggerated and disiapakn to cause an allergic reaction when stimulated by allergens.

When exposure to cat dander, mother and two other children generate classes other antibodies, none of it cause an allergic reaction. In the family members who are not allergic, dander particles are eliminated by the immune system and the cat has no effect on them.

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