Gout is divided into two kinds, namely primary gout and gout sekundar. This division is based on the factors causing uric acid in the body increases. There are two main factors cause a rise of uric acid in the body which causes the primary and secondary causes. The cause of primary gout comes from within the body itself was secondary cause comes from outside the body.
Primary Causes of Uric Acid
The cause is related to the factor of the body seseong but it is not certain. Thought to be caused by genetic factors and hormonal imbalance in the body that causes a metabolic disorder that can lead to increased production of uric acid. It could also be caused by uric acid spending tengganggunaya process of the body because the kidneys more problematic.
Secondary Causes of Uric Acid
The cause is very closely linked to the intake of food that enters the body. Consumption of foods that contain lots of purines as major factors for secondary causes this. Uric acid production increases due to the nutrients we consume high levels of purines. Purine is a compound organic bases that make up nucleic acids (acid nucleus of the cell). He was among the amino acids, the building-blocks of proteins.
Increased production of uric acid can also be due to diseases of the blood (bone marrow disease, polycythemia), drugs (alcohol, cancer drugs, vitamin B12). Other causes are obesity (overweight), skin diseases (psoriasis), high levels of triglycerides. In patients with uncontrolled diabetes are common to both levels of ketone bodies (waste product of fat metabolism) are rising. Ketone bodies were elevated as a cause of gout is also rising.
Risk factors that cause the disease gout is diet, obesity, and ethnicity. In the world, the tribes highest prevalence in the Maori in Australia. The prevalence of the disease Maori uric acid once, while in Indonesia, the highest prevalence in the population of the coast and the highest in the Manado-Minahasa habit or eating fish and drinking alcohol.
Alcohol causes uric acid through urine discharge is reduced so come uric acid in the blood remained. High fish consumption also lead to gout. Intake into the body also affect the levels of uric acid in the blood. Foods that contain high purine substances are converted into uric acid. Purines are particularly high in organ meats, sea food: shrimp, squid, clams, crabs, fish.
IF according to the results of laboratory tests uric acid levels are too high, we need to pay attention to the problem of food. Food and drinks are always consumed is a precursor of uric acid. In obese people, uric acid is usually up while spending less. So for safety, people are usually advised to lose weight.
The most important thing to know is that high uric acid in the blood, without us knowing it will damage the body's organs, especially the kidneys, because the filter will clog. Blockage of the kidney filter will result in the emergence of kidney stones, or could eventually lead to kidney failure.
Uric acid is also a risk factor for coronary heart disease. Allegedly uric acid crystals would damage the endothelium (the inner lining of blood vessels) disease. Therefore, anyone that high uric acid levels should seek to bring it down so that the damage does not spread to the organs of the body.